BCMB Seminar Series

Please join us in our departmental seminar series September through April; no registration required for visitors.

Time and place: Friday afternoons from 1:30 - 2:30 p.m. in ECS 124 (except where noted).

2017

Date Description Presenter Location

Nov 9, 2017 (Thursday)

1:30 - 2:30pm

“Bacterial Communications with the Brain”

Dr. Elaine Tuomanen, Infectious Diseases Department, Children's Infection Defense Center, St. Jude Children's Research Hospital, Memphis, Tennessee

Hosted by: Dr. Caroline Cameron

***BWC A104***

Nov 3, 2017

1:30 - 2:30pm

Dr. Ivan Sadowski

Hosted by: Drs. Juan Ausio and Chris Nelson

ECS 124

Oct 27, 2017

1:30 - 2:30pm

Dr. Lisa Osborne

Hosted by: Dr. Lisa Reynolds

ECS 124

Oct 20, 2017

no seminar

Oct 13, 2017

1:30 - 2:30pm

“Cellular stress triggers the formation of natural amyloid aggregates”

Dr. Timothy Audas, Department of Molecular Biology and Biochemistry, Simon Fraser University

Hosted by: Drs. Perry Howard and Chris Nelson

ECS 124

Oct 6, 2017

no seminar

Sep 29, 2017

1:30 - 2:30pm

“Regulation of Retinal Bipolar Cell Subtype Development by Hedgehog Signaling”

Dr. Robert Chow, Department of Biology, University of Victoria

Hosted by: Dr. John Burke

ECS 124

Sep 22, 2017

1:30 - 2:30pm

“The roles of CDK12 in cancer: a multi-functional kinase that regulates transcription and alternative pre-mRNA splicing”

Dr. Gregg Morin, BC Cancer Agency, Michael Smith Genome Sciences Centre, UBC Department of Medical Genetics

Hosted by: Dr. John Burke

ECS 124

Sep 15, 2017

1:30 - 2:30pm

“Pannexin 1 function and trafficking in the nervous system”

Dr. Leigh Anne Swayne, Division of Medical Sciences, University of Victoria

Hosted by: Dr. John Burke

ECS 124

Apr 28, 2017

1:30 - 2:30pm

“Development of immuno-MALDI mass spectrometry assays for the quantification of PI3K/AKT/mTOR signalling pathway activity to predict patient’s response to targeted cancer therapy in colorectal cancer”

Bjorn Frohlich, PhD Candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Christoph Borchers

CUN 146

Apr 21, 2017

1:30 - 2:30pm

“Personalized immunotherapy based on the genomic and cellular architecture of cancer”

Dr. Brad Nelson, Deeley Research Centre, B.C. Cancer Agency, Victoria, Department of Biochemistry and Microbiology, University of Victoria

Hosted by: Dr. Perry Howard

ECS 124

Apr 5, 2017 (Wednesday)

2:00 - 3:00pm

Lansdowne Department Lecture

“Antimicrobial resistance in Neisseria gonorrhoeae: evolutionary genius and the public health response”

Professor David Lewis, Western Sydney Sexual Health Centre, Marie Bashir Institute for Biosecurity and Infectious Diseases, Sydney Medical School, Westmead, University of Sydney, Australia

Hosted by: The Department of Biochemistry and Microbiology

ECS 116

Apr 4, 2017 (Tuesday)

7:00 - 8:00pm

Lansdowne Public Lecture - free & open to everyone

“The Re-emergence of Untreatable Gonorrhea: A Public Health Nightmare for the 21st Century?”

Professor David Lewis, Western Sydney Sexual Health Centre, Marie Bashir Institute for Biosecurity and Infectious Diseases, Sydney Medical School, Westmead, University of Sydney, Australia

Hosted by: The Department of Biochemistry and Microbiology

Bob Wright Centre, Room A104

Mar 31, 2017

1:30 - 2:30pm

“Controlling Carrageenan Remodelling: A Sulfation Fascination”

Andrew Hettle, PhD Candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Alisdair Boraston

ECS 116

Mar 24, 2017

1:30 - 2:30pm

“As the spindle turns: The control of expansion, fate, and death in progenitor cells”

Dr. Christopher Maxwell, Department of Pediatrics, University of British Columbia, Vancouver

Hosted by: Dr. John Burke

ECS 116

Mar 17, 2017

1:30 - 2:30pm

“Hydroxycinnamoyl esters in Populus, roles in development and defense”

Cuong Le, PhD Candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Christoph Borchers

ECS 116

Mar 10, 2017

1:30 - 2:30pm

“Gas-phase hydrogen/deuterium exchange mass spectrometry: a new approach to glycan structural elucidation”

Dr. Miklos Guttman, Department of Medicinal Chemistry, University of Washington, Seattle, WA

Hosted by: Dr. John Burke

ECS 116

Mar 3, 2017

1:30 - 2:30pm

“Determination of PI3K/AKT/mTOR signaling pathway activity by immuno-MALDI to predict cancer patient outcome to targeted treatment”

Robert Popp, PhD Candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Christoph Borchers

ECS 116

Feb 24, 2017 (2 seminars today)

1:30 - 2:30pm

“Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI-MSI) for Biomolecule Detection and Identification”

Teesha Baker, MSc Student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Christoph Borchers

ECS 116

Feb 24, 2017 (2 seminars today)

1:30 - 2:30pm

“Multiple structural proteomic techniques for the structural elucidation of tau protein oligomerization”

Karl Makepeace, MSc Student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Christoph Borchers

ECS 116

Feb 17, 2017

no seminar - Reading Break

Feb 10, 2017

no seminar

Feb 3, 2017

1:30 - 2:30pm

“Investigation of innate immunity in developing Rana (Lithobates) catesbeiana tadpoles”

Shireen Partovi MSc Student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Caren Helbing

ECS 116

Jan 27, 2017

1:30 - 2:30pm

"Multiple Mechanisms of Transcriptional Regulation"

Dr. Michael S. Kobor, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver

Hosted by: Drs. Chris Nelson and Juan Ausio

ECS 116

Jan 20, 2017

1:30 - 2:30pm

"Endocrine disruption in the developing brain: Emerging ideas and animal models"

Dr. Heather Patisaul, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina

Hosted by: Dr. Caren Helbing

ECS 116

Jan 13, 2017 (2 seminars today)

1:30 - 2:30pm

“Bioinformatic analyses of poxvirus genomes”

Cindy Tu, MSc Student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Chris Upton

ECS 116

Jan 13, 2017 (2 seminars today)

1:30 - 2:30pm

“Identifying novel molecular biomarkers of xenobiotic endocrine disruption using tadpoles of the North American bullfrog Rana (Lithobates) catesbeiana”

Kevin Jackman, MSc Student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Caren Helbing

ECS 116

Jan 6, 2017

1:30 - 2:30pm

"Determining the role(s) of the Ars2/Cap complex in the birth and death of RNAP II transcripts and heterochromatin silencing"

Dr. Perry Howard, Chair, Department of Biochemistry and Microbiology, University of Victoria

Hosted by: The Department of Biochemistry and Microbiology

ECS 116

2016

Date Description Presenter Location

Dec 2, 2016

1:30 - 2:30pm

"Regulation of virulence factor production by the Lyme disease spirochete: Answers lead to more questions"

Dr. Brian Stevenson, Dept. of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky

Hosted by: Dr. Caroline Cameron

ECS 124

Nov 25, 2016

1:30 - 2:30pm

"Developments in Point of Care Diagnostics: From AIDS to Zika"

Dr. Michelle Zaharik, bioLytical™ Laboratories Inc., Richmond, B.C.

Hosted by: Dr. Caroline Cameron

ECS 124

Nov 18, 2016

1:30 - 2:30pm

"Specific, pan-specific or perfectly promiscuous: new chemical tools for studying protein methylation"

Dr. Fraser Hof, Department of Chemistry, University of Victoria

Hosted by: Dr. Perry Howard

ECS 124

Nov 11, 2016

no seminar - Remembrance Day

Nov 4, 2016 (2 seminars today)

1:30 - 2:30pm

“Structural and functional characterization of apicomplexan invasion machinery”

Cameron Powell, MSc Student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Marty Boulanger

ECS 124

Nov 4, 2016 (2 seminars today)

1:30 - 2:30pm

“Molecular mechanisms of human phosphatidylinositol 4 kinase IIIß regulation by host and viral protein complexes”

Jacob McPhail, MSc Student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. John Burke

ECS 124

Oct 28, 2016

no seminar

Oct 24, 2016 (Monday)

1:30 - 2:30pm

Dr. John Vincent, Professor, Department of Psychiatry, University of Toronto

Hosted by: Dr. Juan Ausio

***ELL 061***

Oct 21, 2016

no seminar

Oct 14, 2016

1:30 - 2:30pm

A molecular view of glycan utilization by the human gut microbiota

Dr. Nicole Koropatkin, Assistant Professor, Microbiology & Immunology, University of Michigan Medical School

Hosted by: Dr. Al Boraston

ECS 124

Oct 7, 2016

1:30 - 2:30pm

Addressing the Clinical Proteome with Mass Spectrometric Assays

Dr. Leigh Anderson, Siscapa Assay Technologies; Adjunct Professor, Department of Biochemistry & Microbiology, Univeristy of Victoria

Hosted by: Dr. Terry Pearson

ECS 124

Sept 30, 2016

1:30 - 2:30pm

Chromatin interactions of the Saccharomyces cerevisiae prolyl-isomerase Fpr4

Andrew Leung, PhD Candidate, Department of Biochemistry & Microbiology, Univeristy of Victoria

Hosted by: Dr. Chris Nelson

ECS 124

Sept 23, 2016

1:30 - 2:30pm

“The Metabolic Ecosystem of T cells and Tumors”

Dr. Julian Lum, Deeley Research Centre, B.C. Cancer Agency, Victoria; Assistant Professor (Limited Term), Department of Biochemistry and Microbiology, University of Victoria

Hosted by: Dr. Perry Howard

ECS 124

Sept 16, 2016

1:30 - 2:30pm

“Molecular mechanisms of host cell invasion by apicomplexan parasites”

Dr. Martin Boulanger, Associate Professor, Department of Biochemistry & Microbiology, Univeristy of Victoria

Hosted by: Dr. Perry Howard

ECS 124

August 19, 2016

10:00 - 11:00am

“The highly reduced spliceosome of Cyanidioschyzon merolae: an extremophile provides a simpler model for studying splicing”

Dr. Stephen Rader, Department of Chemistry, University of Northern British Columbia, Prince George, B.C.

Hosted by: Dr. Perry Howard

ECS 124

April 25, 2016

10:30 - 11:30am

"Influenza A virus, stress granules, and host-directed antiviral drugs"

Dr. Denys Khaperskyy, Department of Microbiology and Immunology, Dalhousie University

Hosted by: Dr. Perry Howard

ECS 124

April 21, 2016

10:30 - 11:30am

"Paradigms in microbial metabolism: missing links and surprising consequences"

Dr. Joanne Hobbs, Department of Biochemistry and Microbiology, University of Victoria

Hosted by: Dr. Perry Howard

ECS 116

April 18, 2016

10:30 - 11:30am

"Gut health early in life: the role of our first microbiota"

Dr. Marie-Claire Arrieta, Michael Smith Laboratories, University of British Columbia

Hosted by: Dr. Perry Howard

ECS 124

April 15, 2016

1:30 - 2:30pm

"Defining the essential role of the RSK/YB-1 pathway in breast cancer"

Dr. Sandra Dunn, CEO and Founder, Phoenix Molecular Designs, Vancouver, BC

Hosted by: Dr. John Burke

ECS 124

April 14, 2016

10:30 - 11:30am

"Targeting Chagas disease pathogenesis"

Dr. Laura-Isobel McCall, Center for Discovery and Innovation in Parasitic Disease, University of California, San Diego

Hosted by: Dr. Perry Howard

ECS 124

April 11, 2016

10:30 - 11:30am

"Modulation of host immunity by intestinal helminth parasites and the bacterial microbiota"

Dr. Lisa Reynolds,Michael Smith Laboratories, University of British Columbia

Hosted by: Dr. Perry Howard

ECS 124

April 8, 2016

1:30 - 2:30pm

"The DNA Damage Response: Chromatin and Cancer"

Dr. Kyle M. Miller, Assistant Professor, CPRIT Scholar University of Texas at Austin

Hosted by: Dr. Chris Nelson

ECS 124

April 1, 2016

1:30 - 2:30pm

"Lipid nanoparticle (LNP)-based nucleic acid therapeutics: The development of siRNA and mRNA drugs"

Dr. Ying Tam, Director of Preclinical Research, Acuitas Therapeutics, Vancouver BC

Hosted by: Dr. Doug Briant

ECS 124

March 18, 2016

1:30 - 2:30pm

"Characterizing the prolyl isomerase FKBP25 in ribosome biogenesis"

Geoff Gudavicius, PhD Candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Chris Nelson

ECS 124

March 11, 2016

1:30 - 2:00pm

"Tumour Associated T Cells from High-Grade Serous Ovarian Carcinoma Patients Recognize the Cancer Testis Antigen Lactate Dehydrogenase C"

David Neilson, MSc Student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Julian Lum

ECS 124

March 8, 2016

7 - 9 pm

"The Future of Medicine: From molecularly targeted therapies to gene editing"

A panel of experts from UVic, UBC, the BC Cancer Agency will share their perspective on the future of medicine.

Hosted by: Dr. Perry Howard

ECS 125

An Ideafest Event

March 4, 2016

"Defining the nuclear functions of the proline isomerase FKBP25"

David Dilworth, PhD Candidate Department of Biochemistry & Microbiology, University of Victoria

Hosted by: Dr. Chris Nelson

ECS 124

Feb. 19, 2016

1:30 - 2:00pm

"Investigating the Co-Evolution of Tumor Antigens and the Anti-Tumor Immune Response in High-Grade Serous Carcinoma"

Nicole Little, MSc student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Brad Nelson

ECS 124

Feb. 19, 2016

2:00 - 2:30pm

"Isolation and characterization of marine organic Cu(II) ligands by LC-MS"

Richard L. Nixon, MSc student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Andrew Ross

ECS 124

Feb. 12, 2016

8:30am - 4pm

The 21st Annual Biochemistry and Microbiology Graduate Student Symposium

Invited speakers (see below), graduate student presentations, poster sessions and more

Hosted by BCMB Graduate Students

Bob Wright Centre lobby and A104

Feb. 12, 2016

9:00 - 9:50am

"Applying proteomics in honey bees: understanding basic mechanisms to industrial bee breeding"

Dr. Leonard Foster, Director, Centre for High- Throughput Biology & Professor, Department of Biochemistry & Molecular Biology, University of British Columbia

Hosted by BCMB Graduate Students

BWC A104

Feb. 12, 2016

12:45 - 1:35pm

"Illuminating the mechanisms of vascular repair in the brain during health and disease"

Dr. Craig Brown, Associate Professor, Division of Medical Sciences, University of Victoria

Hosted by BCMB Graduate Students

BWC A104

Feb. 5, 2016

1:30-2:30 p.m.

"Synergy between T- and B- lineage cells in the immune response to cancer"

Dr. David Kroeger, Postdoctoral fellow, Trev and Joyce Deeley Research Centre, BC Cancer Agency

Hosted by Dr. Julian Lum

Conference room #3, Third floor of the Vancouver Island Cancer Centre (2410 Lee Avenue)

Jan. 29, 2016

1:30-2:30 p.m.

"Investigating the structure and function of an autophagy regulatory machinery"

Dr. Calvin Yip, Assistant Professor, Department of Biochemistry & Molecular Biology, University of British Columbia

Hosted by Dr. Marty Boulanger

ECS 124

Jan. 15, 2016

1:30-2:30 p.m.

"Probing the structural and dynamic regulation of lipid signalling in disease"

Dr, Angelika Niemz, Beckman Professor and Director of Research at Keck Graduate Institute, Claremont, CA

Hosted by Dr. Paul Romaniuk

ECS 124

Jan. 8, 2016

1:30-2:00 p.m.

"Understanding lipid kinase misregulation: The role of PI3Kδ mutations in primary immunodeficiency disease"

Gillian Dornan, PhD student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. John Burke

ECS 124

Jan. 8, 2016

2:00-2:30 p.m.

"Advancing mechanistic understanding of the human blood group enzymes"

Susannah Gagnon, MSc student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Stephen Evans

ECS 124

2015

Date Description Presenter Location

May 15, 2015

1:30-2:30 p.m.

"The requirements of ARS2 for RNA processing and retina development"

Mr. Connor O'Sullivan, PhD Candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Perry Howard

ECS 104

July 24, 2015

1:30-2:30 p.m.

"Molecular mechanisms of vector-pathogen interactions: Insights from the tsetse-trypanosome system"

Mr. Ragha Ramaswamy, PhD Candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Marty Boulanger

ECS 108

Sept. 18, 2015

1:30-2:30 p.m.

"Probing the structural and dynamic regulation of lipid signalling in disease"

Dr. John Burke, Assistant Professor, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Perry Howard

ECS 124

Sept. 25, 2015

1:30-2:30 p.m.

"Peptidomics and Secretomics for biomedical applications"

Dr. Peter Verhaert, Analytical Biotechnology & Innovative Peptide Biology, Faculty of Applied Sciences, Delft University of Technology (Netherlands); Faculty of Medicine, Department of Clinical Sciences, Lund University (Sweden); Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Antwerp University (Belgium)

Hosted by Dr. John Burke

ECS 124

Oct. 2, 2015

1:30-2:30 p.m.

"Deciphering the proteome of the syphilis spirochete (T. pallidum ssp. pallidum): insights into pathogenesis and biomarker discovery"

Dr. Kara Osbak, Institute of Tropical Medicine Antwerp, University of Antwerp, Belgium

Hosted by Dr. Caroline Cameron

ECS 124

Oct. 9, 2015

1:30-2:30 p.m.

"Use of temperature sensitive essential genes as a biocontainment mechanism"

Jarek Pankowski, PhD Candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Fran Nano

ECS 124

Oct. 16, 2015

1:30-1:50 p.m.

"Transcriptional Regulation of Citrate Synthase Is Essential for Initiation of Cell Growth"

Sarah MacPherson, MSc student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Julian Lum

ECS 124

Oct. 16, 2015

2:00-2:20 p.m.

"Molecular mechanisms for the Treponema pallidum protein pallilysin (Tp0751) in adhesion to the vascular endothelium"

Karen Lithgow, MSc student, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Caroline Cameron

ECS 124

Oct. 23, 2015

1:30-2:30 p.m.

"Dissecting the metabolism of dietary carbohydrates by intestinal microbes"

Dr. Wade Abbott, Research Scientist, Agriculture and Agri-Food Canada, Lethbridge; Adjunct Professor, Department of Chemistry & Biochemistry, University of Lethbridge

Hosted by Dr. Al Boraston

ECS 124

Nov. 6, 2015

1:30-2:30 p.m.

"A structural basis for cross-reactivity and polyspecificity in germline antibodies"

Ryan Blackler, PhD candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Stephen Evans

ECS 124

Nov. 13, 2015

1:30-2:30 p.m.

"Lifting the (brain) fog: Probing the pathogenesis of Lyme neuroborreliosis"

Dr. Catherine Brissette, Assistant Professor, School of Medicine and Health Sciences, University of North Dakota

Hosted by Dr. Caroline Cameron

ECS 124

Nov. 20, 2015

1:30-2:30 p.m.

"Chromatin oligomers: an in vitro model for interphase chromosome structure and function"

Dr. Jeffrey Hansen, Professor, Department of Biochemistry & Microbiology, Colorado State University

Hosted by Dr. Juan Ausio

ECS 124

Nov. 27, 2015

1:30-2:30 p.m.

"Cell cycle regulation of DNA repair"

Dr. Daniel Durocher, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario

Hosted by Drs. Perry Howard and Chris Nelson

ECS 124

Dec. 4, 2015

1:30-2:30 p.m.

"Using multiple structural proteomic techniques for the characterization of prion protein oligomers"

Jason Serpa, PhD candidate, Department of Biochemistry & Microbiology, University of Victoria

Hosted by Dr. Christoph Borchers

ECS 124