Taylor, John


Phone number: (250) 472-5206
Email: taylorjs@uvic.ca
Department: Biology

Research description:

Research Description

- Bioinformatics and experimental molecular biology
- Gene regulation and genome evolution
- Comparative genomics
- Opsins and olfactory receptors

Expertise Profile
Dr. John Taylor's interest in biology stems from growing up watching nature shows on an old black and white TV.

Today in his lab at the University of Victoria, he studies in animals in a different way. Dr. Taylor works at the level of the genome, studying differences in genes in different species and in different individuals.

Specifically, he studies the associations between the genotype, a given gene or set of genes, and the phenotype, how a gene is expressed -- for example the colour of a dog's fur or a type of human disease.

A recent project studies opsin genes in fish. Opsins are connected to the light receptors in the eye that influence colour vision. Some fish have many more opsins than humans and Dr. Taylor is interested to see how this influences their vision.

From fish to humans, he is also researching the evolution of cancer and how cancer genes differ from diagnosis to chemotherapy to re-occurrence.

Down the road this sort of research could help doctors know when chemotherapy will and will not work before administering it to a patient.

In all his classes, Dr. Taylor conveys to his students how broad the research and application of genetics can be. At the level of the genome, ecology and medicine aren't as dissimilar as they might seem and the opportunities for students to pursue what interests them are almost endless.

Health related research:

In collaboration with the BC Genome Sciences Centre, Dr. Taylor has been using bioinformatics tools to study gene duplication in cancer evolution. With help from the Sharon Stewart Trust, he has been using additional bioinformatics tools to study gene synteny, with the goal of improving our understanding of PAX6 expression.

International research:

Gene and genome duplication research with colleagues in Belgium and Germany.

Countries lived or worked in:

Zimbabwe, Venezuela, Guyana, Sweden, France, Germany

Software development

In Dr. Taylor's lab they develop software tools for surveying DNA sequences.

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