Facility for Biomolecular Sample Preparation

Undergraduate research

Undergraduate research

Lance Bai (BSc. ChemMedSci Major, UVic) and Zoey Warmerdam (Exchange student, University of Applied Science, Leiden, Netherlands) synthesize novel bioactive peptides.

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Graduate research

Graduate research

Ronan Hanley (Chemistry PhD student, UVic) studies biomolecular interactions important in cancer and autoimmune disease.

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Cell and tissue culture

Cell and tissue culture

The FBS has a complete set of facilities for bacterial and mammalian tissue culture.

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Biosample purifications

Biosample purifications

The FBS has infrastructure for the purification and analysis of diverse biological samples. Chakravarthi Simhadri (Chemistry PhD student) synthesizes and purifies novel therapeutics targeting stem-like cancers, and tests their potency using FBS-prepared protein samples.

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Biosafety facilities

Biosafety facilities

The FBS is home to two Biosafety Level 2 rooms and additional biochemical laboratory space for the safe handling of human tissues and fluids, cell cultures, human pathogens, and biomolecules of all kinds.

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Interdisciplinary collaborations

Interdisciplinary collaborations

Wei Li (Chemistry MSc. student) works with collaborators in the Gordon lab from Electrical and Computer Engineering to create nanoparticle-based molecular diagnostics for the early detection of lung and colorectal cancer.

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Facility for Biomolecular Sample Preparation (FBS)

Welcome to the Facility for Biomolecular Sample Preparation (FBS), an open-access user facility spread across two Department of Chemistry Biosafety Level 2 labs in the Bob Wright Centre and the Petch Building. FBS is part of the Centre for Advanced Materials and Related Technology (CAMTEC) at the University of Victoria.

FBS houses a diverse set of equipment for bio-sample preparation, purification, and analysis. This includes a complete set of instruments required for using recombinant E. coli expression to go from gene to purified protein, equipment for characterizing purified proteins, facilities for culturing and studying mammalian cells, an advanced multimode plate reader, and a Biacore surface plasmon resonance (SPR) instrument. Other instruments, including an isothermal titration calorimeter, HPLC, LC-MS, and automated peptide synthesizer are located in adjoining facilities and may be made available on a case-by-case basis.

We offer consistent protocols and hands-on training to all users so that they can become proficient with each of the above techniques. Anyone may apply to use the facility, regardless of discipline, whether for academic or commercial purposes. Users may arrange for training or commission our services directly. Different experiments in the FBS will require different levels of bio-safety certification. Bio-safety training is available through UVic Occupational Health and Safety for those who need it. Please contact us if you think we might be of assistance.