Publications

Recently published neuroscience research conducted in the Division of Medical Science by our faculty, post-doctoral fellows, and graduate students.

Year	Author	Title	Authors
2021	Marie-Eve TremblayLeigh Anne Swayne (DMSC)	Purinergic signaling in nervous system health and disease: Focus on pannexin 1	Sanchez-Arias JC, van der Slagt E, Vecchiarelli HA, Candlish RC, York N, Young PA, Shevtsova O, Juma A, Tremblay MÈ, Swayne LA.
2021	Marie-Eve TremblayLeigh Anne Swayne (DMSC)	A Systematic, Open-Science Framework for Quantification of Cell-Types in Mouse Brain Sections Using Fluorescence Microscopy	Sanchez-Arias JC, Carrier M, Frederiksen SD, Shevtsova O, McKee C, van der Slagt E, Gonçalves de Andrade E, Nguyen HL, Young PA, Tremblay MÈ, Swayne LA.
2021	Leigh Anne Swayne (DMSC)	Treponema pallidum Disrupts VE-Cadherin Intercellular Junctions and Traverses Endothelial Barriers Using a Cholesterol-Dependent Mechanism	Lithgow KV, Tsao E, Schovanek E, Gomez A, Swayne LA, Cameron CE.
2021	Craig Brown (DMSC)	New Vistas in Stroke Research: Targeting the endothelium to restore blood flow	Reeson P and Brown CE.
2021	Craig Brown (DMSC)	Microvascular basis of cognitive impairment in type 1 diabetes	Sharma S and Brown CE.
2021	Craig Brown (DMSC)	Invasion of Phagocytic Galectin-3 expressing macrophages in the diabetic brain disrupts vascular repair	Mehina EMF, Taylor S, Boghozian R, White E, Choi S, Cheema M, Korbelin J, Brown
2021	Craig Brown (DMSC)	Longitudinal functional imaging of VIP interneurons reveals sup-population specific effects of stroke that can be rescued with chemogenetic therapy.	Motaharinia M, Gerrow G, Boghozian R, White E, Choi S, Delaney K, and Brown CE.
2021	Brian Christie (DMSC)	Exercise hormone irisin is a critical regulator of cognitive function	MR Islam, S Valaris, MF Young, EB Haley, R Luo, SF Bond, S Mazuera, RR Kitchen, BJ Caldarone, LEB Bettio, BR Christie, AB Schmider, RJ Soberman, A Besnard, MP Jedrychowski, H Kim, H Tu, E Kim, SH Choi, RE Tanzi, BM Spiegelman, CD Wrann.
2021	Brian Christie (DMSC)	Heading in the Right Direction: A Critical Review of Studies Examining the Effects of Heading in Soccer Players	Snowden, T. Reid, H. Kenny, RA. McQuarrie, A. Stuart-Hill, L. Garcia-Barrera, M. Gawryluk, J. Christie, BR.
2021	Brian Christie (DMSC)	Effects of prenatal ethanol exposure on choline-induced long-term depression in the hippocampus	EL Grafe, CJ Fontaine, JD Thomas, BR Christie.
2021	Brian Christie (DMSC)	Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice	Thomas H Lee, Ahadullah, Brian R Christie, Kangguang Lin, Parco Ming-fai Siu, Li Zhang, Ti-fei Yuan, Pragya Komal, Aimin Xu, Kwok-fai So, Suk-yu Yau.
2021	Patrick Nahirney (DMSC)Brian Christie (DMSC)	Unlocking the brain: A new method for Western blot protein detection from fixed brain tissue	Jonathan S Thacker, Delaney Andersen, Stanley Liang, Natalia Zieniewicz, Juan S Trivino-Paredes, Patrick C Nahirney, Brian R Christie.
2021	Brian Christie (DMSC)	Understanding Changes in Hippocampal Interneurons Subtypes in the Pathogenesis of Alzheimer's Disease: A Systematic Review	H.M.O. Reid, N. Chen-Mack, T. Snowden, B.R. Christie.
2021	Brian Christie (DMSC)	Prenatal alcohol and cannabis exposure can have opposing and region-specific effects on parvalbumin interneuron numbers in the hippocampus	HMO. Reid,TM. Snowden,I Shkolnikov, KR Breit, C Rodriguez, JD Thomas, BR Christie.
2021	Patrick Nahirney (DMSC)Brian Christie (DMSC)	Acute Δ9-tetrahydrocannabinol prompts rapid changes in cannabinoid CB1 receptor immunolabeling and subcellular structure in CA1 hippocampus of young adult male mice	Itziar Bonilla-Del Río, Nagore Puente, Amaia Mimenza, Almudena Ramos, Maitane Serrano, Leire Lekunberri, Inmaculada Gerrikagoitia, Brian R Christie, Patrick C Nahirney, Pedro Grandes.
2020	Marie-Eve Tremblay	An antibody for analysis of autophagy induction	Tian W, Alsaadi R, Guo Z, Kalinina A, Carrier M, Tremblay ME, Lacoste B, Lagace D, and Russell RC.
2020	Marie-Eve Tremblay	Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington's disease pathology	avage JC, St-Pierre MK, Carrier M, El Hajj H, Weiser Novak S, Sanchez MG, Cicchetti F, and Tremblay ME.
2020	Marie-Eve Tremblay	Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice	Ouellette J, Toussay X, Comin CH, da F. Costa L, Ho M, Lacalle-Aurioles M, Freitas-Andrade M, Liu QY, Leclerc S, Pan Y, Liu Z, Thibodeau JF, Yin M, Carrier M, Morse CJ, Van Dyken P, Bergin CJ, Baillet S, Kennedy CR, Tremblay ME, Benoit YD, Stanford WL, Burger D, Stewart DJ, and Lacoste B.
2020	Marie-Eve Tremblay	Neuronal hyperactivity dampens neuronal intrinsic excitability and stress responsiveness during chronic stress	Matovic S, Ichiyama A, Igarashi H, Salter E, Sunstrum J, Wang XF, Henry M, Kuebler E, Vernoux N, Martinez-Trujillo J, Tremblay ME, and Wataru I.
2020	Marie-Eve Tremblay	Platelets release mitochondrial antigens in systemic lupus erythematosus	Melki I, Allaeys I, Tessandier N, Lévesque T, Cloutier N, Laroche A, Vernoux N, Becker Y, Hadrien Benk-Fortin, Julien AS, Zufferey A, Labelle ER, Poirier G, Patey N, Soulet D, Tremblay ME, McKenzie S, Lood C, Fortin PR, and Boilard E.
2020	Marie-Eve Tremblay	Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration	Gratuze M, Leyns CEG, Sauerbeck AD, St-Pierre MK, Xiong M, Kim N, Remolina Serrano J, Tremblay ME, Kummer TT, Colonna M, Ulrich JD, and Holtzman DM.
2020	Marie-Eve Tremblay	Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high fat diet	Bordeleau M, Lacabanne C, Fernández de Cossío L, Vernoux N, Savage JC, González-Ibáñez F, and Tremblay ME.
2020	Marie-Eve Tremblay	Levodopa partially rescues microglial numerical, morphological, and phagolysosomal alterations in a monkey model of Parkinson’s disease.	Lecours C St-Pierre MK, Picard K, Bordeleau M, Bourque M, Awogbindin IO, Benadjal A, Gonzalez Ibanez F, Gagnon D, Cantin L, Parent M, Di Paolo T, and Tremblay ME.
2020	Marie-Eve Tremblay	Alterations in intrinsic and synaptic properties of hippocampal CA1 VIP interneurons during aging	Francavilla R, Guet-McCreight A, Amalyan S, Hui CW, Topolnik D, Michaud F, Marino B, Tremblay ME, Skinner FK, and Topolnik K.
2020	Marie-Eve Tremblay	Sex differences of microglia and synapses in the hippocampal dentate gyrus of adult mouse offspring exposed to maternal immune activation	Hui CW, Vecchiarelli HA, Gervais E, Luo X, Michaud F, Scheefhals L, Bisht K, Sharma K, Topolnik L, and Tremblay ME.
2020	Marie-Eve Tremblay	Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the developing brain	Madore C, Leyrolle Q, Morel L, Delpech JC, Greenhalgh AD, Lacabanne C, Bosch-Bouju C, Bourel J, Thomazeau A, Hopperton KE, Beccari S, Sere A, Aubert A, De Smedt-Peyrusse V, Lecours C, Bisht K, Fourgeaud L, Gregoire S, Bretillon L, Grant NJ, Badaut J, Gressens P, Sierra A, Butovsky O, Tremblay ME, Bazinet RP, Joffre C, Nadjar A, and Layé S.
2020	Marie-Eve Tremblay	The Intellicage system provides a reproducible and standardized method to assess behavioral changes in cuprizone-induced demyelination mouse model. Behavioral Brain Research	Cisbani G, Poggini S, Laflamme N, Pons V, Tremblay ME, Branchi I, and Rivest S.
2020	Leigh Anne Swayne (DMSC)	Ankyrin-B p.S646F undergoes increased proteasome degradation and reduces cell viability in the H9c2 rat ventricular cardiomyoblast cell line	Chen L, Choi CSW, Sanchez-Arias JC, Arbour LT, Swayne LA.
2020	Leigh Anne Swayne (DMSC)	Identification of the Neuroinvasive Pathogen Host Target, LamR, as an Endothelial Receptor for the Treponema pallidum Adhesin Tp0751	Lithgow KV, Church B, Gomez A, Tsao E, Houston S, Swayne LA, Cameron CE.
2020	Leigh Anne Swayne (DMSC)	Consideration of Pannexin 1 channels in COVID-19 pathology and treatment	Swayne LA, Johnstone SR, Ng CS, Sanchez-Arias JC, Good ME, Penuela S, Lohman AW, Wolpe AG, Laubach VE, Koval M, Isakson BE.
2020	Leigh Anne Swayne (DMSC)	PANX1 in inflammation heats up: New mechanistic insights with implications for injury and infection	Sanchez Arias JC, Wicki-Stordeur LE, Candlish RC, van der Slagt E, Paci I, Rao PPN, MacVicar BA, Swayne LA.
2020	Leigh Anne Swayne (DMSC)	Pannexin 1 Regulates Dendritic Protrusion Dynamics in Immature Cortical Neurons	Sanchez-Arias JC, Candlish RC, van der Slagt E, Swayne LA.
2020	Leigh Anne Swayne (DMSC)	ATP triggers macropinocytosis that internalizes and is regulated by PANX1	Boyce AJK, van der Slagt E, Sanchez-Arias JC, Swayne LA.
2020	Craig Brown (DMSC)	Susceptibility to capillary plugging can predict brain region specific vessel loss with aging	Schager B and Brown CE.
2019	Patrick Nahirney (DMSC)	High-resolution immunoelectron microscopy techniques for revealing distinct subcellular type 1 cannabinoid receptor domains in brain	Puente, N., I. Bonilla-Del Río, S. Achicallende, P.C. Nahirney and P. Grandes.
2019	Patrick Nahirney (DMSC)Brian Christie (DMSC)	Endocannabinoid long-term depression revealed at medial perforant path excitatory synapses in the dentate gyrus	Peñasco S, Rico-Barrio I, Puente N, Gómez-Urquijo SM, Fontaine CJ, Egaña-Huguet J, Achicallende S, Ramos A, Reguero L, Elezgarai I, Nahirney PC, Christie BR, Grandes P.
2019	Brian Christie (DMSC)Patrick Nahirney (DMSC)	Acute slice preparation for electrophysiology increases spine numbers equivalently in the male and female juvenile hippocampus: a DiI labeling study	Trivino-Paredes JS, Nahirney PC, Pinar C, Grandes P, Christie BR.
2019	Brian Christie (DMSC)Patrick Nahirney (DMSC)	Intermittent ethanol exposure during adolescence impairs cannabinoid type 1 receptor-dependent long-term depression and recognition memory in adult mice	Peñasco S, Rico-Barrio I, Puente N, Fontaine CJ, Ramos A, Reguero L, Gerrikagoitia I, de Fonseca FR, Suarez J, Barrondo S, Aretxabala X, García Del Caño G, Sallés J, Elezgarai I, Nahirney PC, Christie BR, Grandes P.
2019	Patrick Nahirney (DMSC)	Time and exposure to serotonin affect releasability of recycled vesicles at crayfish claw opener muscle synapses	Bilkey J, Nahirney PC, Delaney KR.
2019	Hector Caruncho (DMSC)Lisa Kalynchuk (DMSC)	Exploring the Potential Antidepressant Mechanisms of TNFα Antagonists.	Brymer KJ, Romay-Tallon R, Allen J, Caruncho HJ, Kalynchuk LE.
2019	Hector Caruncho (DMSC)Lisa Kalynchuk (DMSC)	Patterns of Membrane Protein Clustering in Peripheral Lymphocytes as Predictors of Therapeutic Outcomes in Major Depressive Disorder	Caruncho HJ, Rivera-Baltanas T, Romay-Tallon R, Kalynchuk LE, Olivares JM.
2019	Hector Caruncho (DMSC)Lisa Kalynchuk (DMSC)	Novel Approaches to the Neuropharmacology of Mood Disorders. Front Pharmacol	Caruncho HJ, Kalynchuk LE, Loza MI, Olivares JM.
2019	Leigh Anne Swayne (DMSC)Craig Brown (DMSC)	Pannexin 1 regulates network ensembles and dendritic spine development in cortical neurons	Sanchez-Arias JC, Liu M, Choi CSW, Ebert SN, Brown CE, Swayne LA.