Fetal Alcohol Syndrome

Christie Lab Publications

• Fontaine CJ, Patten AR, Sickmann HM, Helfer JL, Christie BR. Effects of pre-natal alcohol exposure on hippocampal synaptic plasticity: Sex, age and methodological considerations. Neurosci Biobehav Rev. February 2016. doi:10.1016/j.neubiorev.2016.02.014.
• Patten AR, Sawchuk S, Wortman RC, Brocardo PS, Gil-Mohapel J, Christie BR. Prenatal ethanol exposure impairs temporal ordering behaviours in young adult rats. Behav Brain Res. 2016;299:81-89. doi:10.1016/j.bbr.2015.11.032.
• Helfer JL, White ER, Christie BR. Prenatal ethanol (EtOH) exposure alters the sensitivity of the adult dentate gyrus to acute EtOH exposure. Alcohol Clin Exp Res. 2014;38(1):135-143. doi:10.1111/acer.12227.
• Sickmann HM, Patten AR, Morch K, et al. Prenatal ethanol exposure has sex-specific effects on hippocampal long-term potentiation. Hippocampus. 2014;24(1):54-64. doi:10.1002/hipo.22203.
• Gil-Mohapel J, Titterness AK, Patten AR, et al. Prenatal ethanol exposure differentially affects hippocampal neurogenesis in the adolescent and aged brain. Neuroscience. 2014;273:174-188. doi:10.1016/j.neuroscience.2014.05.012.
• Patten AR, Fontaine CJ, Christie BR. A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors. Front Pediatr. 2014;2:93. doi:10.3389/fped.2014.00093.
• Patten AR, Brocardo PS, Christie BR. Omega-3 supplementation can restore glutathione levels and prevent oxidative damage caused by prenatal ethanol exposure. J Nutr Biochem. 2013;24(5):760-769. doi:10.1016/j.jnutbio.2012.04.003.
• Patten AR, Sickmann HM, Dyer RA, Innis SM, Christie BR. Omega-3 fatty acids can reverse the long-term deficits in hippocampal synaptic plasticity caused by prenatal ethanol exposure. Neurosci Lett. 2013;551:7-11. doi:10.1016/j.neulet.2013.05.051.
• Patten AR, Gil-Mohapel J, Wortman RC, Noonan A, Brocardo PS, Christie BR. Effects of Ethanol Exposure during Distinct Periods of Brain Development on Hippocampal Synaptic Plasticity. Brain Sci. 2013;3(3):1076-1094. doi:10.3390/brainsci3031076.
• Patten AR, Brocardo PS, Sakiyama C, et al. Impairments in hippocampal synaptic plasticity following prenatal ethanol exposure are dependent on glutathione levels. Hippocampus. 2013;23(12):1463-1475. doi:10.1002/hipo.22199.
• Patten A, Brocardo PS, Gil-Mohapel J, Christie BR. Oxidative Stress in Fetal Alcohol Spectrum Disorders – Insights for the Development of Antioxidant-Based Therapies. In: Systems Biology of Free Radicals and Anti-Oxidants. ; 2013:23. doi:DOI 10.1007/978-3-642-30018-9_37.
• Titterness AK, Christie BR. Prenatal ethanol exposure enhances NMDAR-dependent long-term potentiation in the adolescent female dentate gyrus. Hippocampus. 2012;22(1):69-81. doi:10.1002/hipo.20849.
• Brocardo PS, Boehme F, Patten A, Cox A, Gil-Mohapel J, Christie BR. Anxiety- and depression-like behaviors are accompanied by an increase in oxidative stress in a rat model of fetal alcohol spectrum disorders: Protective effects of voluntary physical exercise. Neuropharmacology. 2012;62(4):1607-1618. doi:10.1016/j.neuropharm.2011.10.006.
• Helfer JL, White ER, Christie BR. Enhanced deficits in long-term potentiation in the adult dentate gyrus with 2nd trimester ethanol consumption. PLoS One. 2012;7(12):e51344. doi:10.1371/journal.pone.0051344.
• Brocardo PS, Gil-Mohapel J, Christie BR. The role of oxidative stress in fetal alcohol spectrum disorders. Brain Res Rev. 2011;67(1-2):209-225. doi:10.1016/j.brainresrev.2011.02.001.
• Gil-Mohapel J, Boehme F, Patten A, et al. Altered adult hippocampal neuronal maturation in a rat model of fetal alcohol syndrome. Brain Res. 2011;1384:29-41. doi:10.1016/j.brainres.2011.01.116.
• Gil-Mohapel J, Boehme F, Kainer L, Christie BR. Hippocampal cell loss and neurogenesis after fetal alcohol exposure: insights from different rodent models. Brain Res Rev. 2010;64(2):283-303. doi:10.1016/j.brainresrev.2010.04.011.
• Titterness AK, Christie BR. Long-term depression in vivo: effects of sex, stress, diet, and prenatal ethanol exposure. Hippocampus. 2008;18(5):481-491. doi:10.1002/hipo.20407.