Tremblay and lab co-edits, authors chapters in new microglia book
Dr. Marie-Ève Tremblay (pictured) and her lab played critical roles in the creation of Microglia – Physiology, Pathophysiology and Therapeutic Potential, a new book released earlier this year that covers all aspects of the brain’s resident immune cells.
Most significantly, Tremblay co-edited the book with Dr. Alex Verkhratsky (University of Manchester). Tremblay says she recruited her colleague for his world expertise in the field of glial biology, as well as his extensive experience with authoring, editing and publishing of scientific books.
The book introduces readers to microglia, as well as shares the latest discoveries in the microglial research field, in a comprehensive collection of chapters written by top specialists across five continents.
“I learned a lot from everyone involved in the project,” Tremblay says. “It was highly rewarding, though sometimes challenging—considering the high number of chapters and authors.”
Included in the list of authors are Tremblay and the trainees in her lab. They contributed to several chapters in the book, including those on microglia in neurodevelopmental and neuropsychiatric disorders, neurodegenerative diseases, and sleep disorders; microglia and the microbiome-gut-brain axis; adult neurogenesis of learning and memory; and the general pathophysiology of microglia.
The new book can be seen as a sort of expansion on Microglia in Health and Disease, a 2014 book on the subject Tremblay co-edited with Dr Amanda Sierra (Achucarro Basque Center and University of Basque Country). “The two books reflect the exponential growth of the microglia field,” says Tremblay. “The first book had 19 chapters, and the new one has 35! There is so much information to share. These cells have emerged as critical for brain formation, maturation, activity, plasticity, and integrity, as well as behaviour and cognition, across the lifespan. They are also considered the future of neurological health.”
Microglia – Physiology, Pathophysiology and Therapeutic Potential has been viewed over 24,000 times since its release in September 2024.