Clay Holroyd

Clay Holroyd

Ph.D. 2001 (Illinois at Urbana-Champaign) joined Department in 2004

Office: COR A272

My primary scientific interest concerns determining the computational function of a brain area called anterior cingulate cortex. Together with colleagues, I have proposed that anterior cingulate cortex selects and sustains extended sequences of effortful behaviour – for example, how we decide to jog up a steep mountain and then actually follow through with it. To get at this issue I follow a "converging methods" approach involving electroencephalography, functional magnetic resonance imaging, and computational modelling.


  • Neurobiological mechanisms of cognitive control and decision making

Representative publications

Holroyd, C. B., Ribas-Fernandes, J. J. F., Shahnazian, D., Silvetti, M., & Verguts, T. (2018). Human midcingulate cortex encodes distributed representations of task progress. Proceedings of the National Academy of Sciences of the United States of America, 115, 6398–6403.

Hyman, J. M., Holroyd, C. B., & Seamans, J. K. (2017). A novel neural prediction error found in anterior cingulate cortex ensembles. Neuron, 95, 447-456.

Holroyd, C. B., & Umemoto, A. (2016). The research domain criterion framework: The case for anterior cingulate cortex. Neuroscience and Biobehavioral Reviews, 71, 418-443.

Holroyd, C. B., & McClure, S. M. (2015). Hierarchical control over effortful behavior by rodent medial frontal cortex: A computational model. Psychological Review, 122, 54-83.