Dr. Paul Romaniuk

Dr. Paul Romaniuk
Biochemistry and Microbiology

BSc, PhD (McMaster)

Area of expertise

DNA and RNA-based isothermal amplification assays

Research interests

My research focuses on the development of novel point-of-care diagnostic tests for major bacterial and viral pathogens affecting hundreds of millions of people in the developing world. Our approach is a mix of basic science (design principles of isothermal amplification reactions) and implementation (diagnostic tests). In collaboration with laboratories in the United States and China, my research team has been involved in the development of rapid, simple, low-cost isothermal amplifcation-based tests for TB, HIV viral load, Chlamydia, hepatitis C and polio. We believe in the concept of “molecular testing anywhere, anytime” and have already developed assays that require no cold storage of reagents, no specialized lab equipment, no access to electricity; they can literally be done under the village tree in remote locations.

Our recent research has been directed to moving nucleic acid based laboratory tests for infectious diseases into personal use devices that can be used in a home environment. In collaboration with Arete Biosciences, we are developing a home test system for detecting and identifying respiratory viral infections (covid, flu, RSV) and for detecting and identifying STIs (Chlamydia, Gonorrhea).