In the tabbed table below, you will find:
- faculty - professors in the department
- adjunct faculty - external experts with close affiliation with the department
- staff: general office, laboratory instructors, co-op, biotechnical support and central services
- emeritus faculty - retired faculty members still active with the department
Biophysical and biochemical studies of DNA-protein interactions involved in chromatin assembly and gene expression.
Protein-carbohydrate recognition using molecular biological, biochemical, biophysical, and structural methods.
Application of mass spectrometry, proteomics, photoaffinity labelling, and molecular modelling to determine protein structure.
Structural basis of host-pathogen and vector-pathogen interactions; structure-guided design of small molecule therapeutics and vaccines.
Structural and dynamic studies investigating the regulation of lipid signalling enzymes and their role in human disease.
Biochemistry and cell biology of signaling in early animal development.
Bioinformatic, genomic and proteomic approaches to studying the pathogenic mechanisms of spirochetes.
Structural biology of protein-carbohydrate recognition; x-ray crystallography and scientific visualisation.
The effect of environmental pollutants on hormonal signalling in development and disease.
RNA processing in stem cells, Regulation of Pax6 by miRNA, and rewiring of tyrosine pathway in cancer.
Immunometabolism; understand the metabolic roles of autophagy in cancer and T cell survival, development of immune-based treatment combinations with radiation (ovary, breast, prostate, rectal).
The goal of our research is to develop genome engineering tools for generating temperature-sensitive (TS) microbial strains. One application is developing attenuated pathogens that can be used as live vaccine strains. We use directed evolution of native essential genes of mesophiles to change them to produce a TS product with a defined and non-reverting property. We also engineer genetic circuits that use a TS repressor protein to control a lethal gene in a mesophile.
Immune response to cancer, immunotherapy, T cell biology, cytokines, signal transduction and cell cycle regulation. Director of the Trev and Joyce Deeley Research Centre, BC Cancer Agency.
Application of molecular and systems-biology approaches to the study of chromatin regulatory pathway in yeast and mammalian cells. Current areas of investigation include transcription, RNA metabolism and DNA repair pathways involved in normal and cancer biology.
Design and optimization of DNA and RNA-based isothermal amplification assays. Development of novel nucleic acid based point-of-care diagnostic tests to major pathogens in low resource countries.
Viral bioinformatics and computer technologies to analyze viral genomes.
Dr. N. Leigh Anderson, BA, PhD (Cambridge)
Visit Dr. Anderson's web page
Research interests: Plasma Proteome
Human plasma proteomics and biomarkers of disease and quantitative mass spectrometry.
Research Interests: Glycobiology
Structure, function and mechanisms of enzymes in glycome assembly and degradation.
Application of mass spectrometry and peptide biochemistry to structure and mechanisms of neurodegenerative proteins; pathophysiological protein modification; vaccine chemistry; structure and epitope analysis of therapeutic antibodies; affinity-mass spectrometry of biopolymer interaction epitopes; mass spectrometric elucidation of oligomerisation/truncation pathways and structures of "misfolding"/aggregating proteins in neurodegenerative diseases.
Application of mass spectrometry and associated techniques to marine biogeochemistry and proteomics, including the identification of metal-binding compounds and modified proteins involved in stress, disease, and the biological uptake of essential trace elements.
Molecular genetics of breast cancer. Director of the Tumour Tissue Repository at the Deeley Cancer Research Centre, BC Cancer Agency.
Cellular immunity and immune responses to peptide eptitopes, and vaccine development for cervical cancer.
General Office Petch 207
Margaret Blake, Administrative Officer
Deb Penner, Chair's Assistant
Melinda Powell, Graduate Program Coordinator
Barb Currie, Senior Microbiology Lab Instructor
Melissa Doyle, MICR 200 Lab Instructor
Janice Keliher, BCMB 301 Lab Instructor
Val Kerr, BCMB 406 Lab Instructor
Allison Maffey, BCMB 301 Lab Instructor
Sheila Potter, MICR 200 Lab Instructor
Glen Pryhitka, Senior Biochemistry Lab Instructor
Erika Wall, BCMB 406 Lab Instructor
Adrienne White, BCMB 301 Lab Instructor
Co-op, Biochemistry & Microbiology
Rozanne Poulson, Co-op Coordinator
Biotechnical Support Centre Petch 257
Stephen Horak, Electronics Technician
Scott Scholz, Electronics Technician
Central Services Petch 153
Mary Anne Cunningham, Laboratory Assistant
Ellen Busby, Laboratory Assistant
Dr. Tom Buckley, Professor Emeritus
Dr. Ed Ishiguro, Professor Emeritus
Dr. Bob Olafson, Professor Emeritus
Pathogenesis of trypanosomes parasites using antibody-based technologies, and antibody enrichment techniques for quantitative mass spectrometry.
Dr. Verner Paetkau, Professor Emeritus